Honolulu Chapter

The Immune System is Really Amazing (and Designed) | Uncommon Descent

November 1, 2017

“…So, where is the randomness? Well, within the CDR, as best as we can figure, the immune system generates random changes. Is that really a random mutation, though? It has excluded 99.99993% of the genome and focused on the 0.00007% that it knows needs changing. What I tell people is that I will be happy to agree with them that this process is 0.00007% random if they will agree with me that it is 99.99993% designed. That usually ends the conversation.What’s also interesting is that the cell itself starts and stops the process as needed. That is, these aren’t just happenstance mutations – the cell actively knows it needs mutations, and activates a system to produce them, then produces them within the span of 2,000 base pairs that it knows is likely to produce benefit, and then stops once it finds a benefit (it’s actually closer to 500 base pairs that get significant mutations, but there are a few rare mutations farther into the gene)…”

Source: The Immune System is Really Amazing (and Designed) | Uncommon Descent

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